User profiles for J. Yang

Jian Yang

Prof. of Computer Science, Nanjing University of Science and Technology
Verified email at
Cited by 14911


…, L Tierney, JYH Yang, J Zhang - Genome …, 2004 -
The Bioconductor project is an initiative for the collaborative creation of extensible software
for computational biology and bioinformatics. The goals of the project include: fostering
collaborative development and widespread use of innovative software, reducing barriers to …

…, YL Wu, S Thongprasert, CH Yang… - … England Journal of …, 2009 - Mass Medical Soc
Background Previous, uncontrolled studies have suggested that first-line treatment with
gefitinib would be efficacious in selected patients with non–small-cell lung cancer. Methods
In this phase 3, open-label study, we randomly assigned previously untreated patients in …

J Yang, X Liu, K Bhalla, CN Kim, AM Ibrado… - …, 1997 -
Bcl-2 is an integral membrane protein located mainly on the outer membrane of
mitochondria. Overexpression of Bcl-2 prevents cells from undergoing apoptosis in
response to a variety of stimuli. Cytosolic cytochrome c is necessary for the initiation of the …


…, M Shipitsin, LL Campbell, K Polyak, C Brisken, J Yang… - Cell, 2008 - Elsevier
The epithelial-mesenchymal transition (EMT) is a key developmental program that is often
activated during cancer invasion and metastasis. We here report that the induction of an
EMT in immortalized human mammary epithelial cells (HMLEs) results in the acquisition of …


…, BT Sherman, DA Hosack, J Yang… - Genome …, 2003 -
The distributed nature of biological knowledge poses a major challenge to the interpretation
of genome-scale datasets, including those derived from microarray and proteomic studies.
This report describes DAVID, a web-accessible program that integrates functional genomic …

J Yang, D Zhang, AF Frangi… - IEEE transactions on …, 2004 -
In this paper, a new technique coined two-dimensional principal component analysis
(2DPCA) is developed for image representation. As opposed to PCA, 2DPCA is based on
2D image matrices rather than 1D vectors so the image matrix does not need to be …


X Liu, CN Kim, J Yang, R Jemmerson, X Wang - Cell, 1996 - Elsevier
A cell-free system based on cytosols of normally growing cells is established that
reproduces aspects of the apoptotic program in vitro. The apoptotic program is initiated by
addition of dATP. Fractionation of cytosol yielded a 15 kDa protein that is required for in vitro …

…, P Rota, B Fields, J DeRisi, JY Yang… - … England Journal of …, 2003 - Mass Medical Soc
Background A worldwide outbreak of severe acute respiratory syndrome (SARS) has been
associated with exposures originating from a single ill health care worker from Guangdong
Province, China. We conducted studies to identify the etiologic agent of this outbreak …


J Yang, SA Mani, JL Donaher, S Ramaswamy… - cell, 2004 - Elsevier
Metastasis is a multistep process during which cancer cells disseminate from the site of
primary tumors and establish secondary tumors in distant organs. In a search for key
regulators of metastasis in a murine breast tumor model, we have found that the transcription …

…, X Wang, Y Zhang, J Hu, J Wang, S Liu, J Yang… - …, 2002 -
We have produced a draft sequence of the rice genome for the most widely cultivated
subspecies in China, Oryza sativa L. ssp. indica, by whole-genome shotgun sequencing.
The genome was 466 megabases in size, with an estimated 46,022 to 55,615 genes …