…, JD Salamone, JD Van Hoomissen… - …, 2006 - Wiley Online Library
Voluntary physical activity and exercise training can favorably influence brain plasticity by
facilitating neurogenerative, neuroadaptive, and neuroprotective processes. At least some of
the processes are mediated by neurotrophic factors. Motor skill training and regular exercise …

JD Salamone, M Correa, A Farrar, SM Mingote - Psychopharmacology, 2007 - Springer
Background Over the last several years, it has become apparent that there are critical
problems with the hypothesis that brain dopamine (DA) systems, particularly in the nucleus
accumbens, directly mediate the rewarding or primary motivational characteristics of natural …

JD Salamone - Behavioural brain research, 1994 - Elsevier
In recent years, considerable emphasis has been placed upon the putative role of nucleus
accumbens dopamine systems in appetitive motivation and positive reinforcement.
However, considerable evidence indicates that brain dopamine in general, and nucleus …

JD Salamone, MS Cousins, BJ Snyder - Neuroscience & Biobehavioral …, 1997 - Elsevier
Nucleus accumbens (DA) has been implicated in a number of different behavioral functions,
but most commonly it is said to be involved in “reward” or “reinforcement”. In the present
article, the putative reinforcement functions of accumbens DA are summarized in a manner …

JD Salamone, M Correa - Behavioural brain research, 2002 - Elsevier
Abstract Although the Skinnerian 'Empirical Law of Effect'does not directly consider the
fundamental properties of stimuli that enable them to act as reinforcers, such considerations
are critical for determining if nucleus accumbens dopamine systems mediate reinforcement …


JD Salamone, M Correa - Neuron, 2012 - Elsevier
Nucleus accumbens dopamine is known to play a role in motivational processes, and
dysfunctions of mesolimbic dopamine may contribute to motivational symptoms of
depression and other disorders, as well as features of substance abuse. Although it has …

JD Salamone, M Correa, SM Mingote… - Current opinion in …, 2005 - Elsevier
According to the dopamine (DA) hypothesis of reward, DA systems in the brain, particularly
in the nucleus accumbens, are thought to directly mediate the rewarding or primary
motivational characteristics of natural stimuli such as food, water and sex, as well as various …

JD Salamone, MS Cousins, S Bucher - Behavioural brain research, 1994 - Elsevier
Two experiments were conducted to study the role of dopamine in the performance of a
novel cost/benefit procedure. Rats were trained on a T-maze task in which one arm
contained a high reinforcement density (4× 45 mg Bioserve pellets) and the other arm …

JD Salamone, M Correa, S Mingote… - Journal of Pharmacology …, 2003 - ASPET
For several decades, it has been suggested that dopamine (DA), especially in nucleus
accumbens, mediates the primary reinforcing characteristics of natural stimuli such as food,
as well as drugs of abuse. Yet, several fundamental aspects of primary food reinforcement …

JD Salamone, RE Steinpreis, LD McCullough… - …, 1991 - Springer
An important aspect of motivated behavior is that organisms will perform complex
instrumental behaviors to gain access to stimuli such as food. In the present study, food-
deprived rats were tested in an operant chamber in which the animals had a choice between …