TABLE 3

Initial and final parameter estimates and their corresponding precision (CV%)

ParameterInitial EstimateFinal EstimateCV%
Ka (min−1)0.010.0188
K (min−1)0.050.06319
F*10.8611
kout (min−1)0.30.138
nH22.014
SD50 (μg)1–101.822
Smax22.05